EntrezGene = 1022

ID: 1022
ApprovedSymbol: CDK7
EntrezGene: 1022
UniGeneID: Hs.184298
HugoName: cyclin-dependent kinase 7
UniGeneName: Cyclin-dependent kinase 7
GeneOntologyID: GO:0000718
ENSG: ENSG00000134058
ENSP: ENSP00000256443
KEGGID: hsa+1022
ApprovedSymbol2: CDK7
Evidence: EXP
Chromosome: 5q12.1
Status: Approved
Aliases: CAK1, CDKN7, MO15, STK1
StringSymbol: CDK7
StringName: cyclin-dependent kinase 7; Cyclin-dependent kinases (CDKs) are activated by the binding to a cyclin and mediate the progression through the cell cycle. Each different complex controls a specific transition between two subsequent phases in the cell cycle. CDK7 is the catalytic subunit of the CDK-activating kinase (CAK) complex, a serine-threonine kinase. CAK activates the cyclin-associated kinases CDC2/CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive [...]

Related Pathways:

>>[Reactome] Mitotic M-M/G1 Phases
>>[Reactome] Mismatch Repair
>>[Reactome] S Phase
>>[Reactome] Cell Cycle, Mitotic

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