EntrezGene = 1026

ID: 1026
ApprovedSymbol: CDKN1A
EntrezGene: 1026
HGNC: HGNC:1784
UniGeneID: Hs.370771
HugoName: cyclin-dependent kinase inhibitor 1A (p21, Cip1)
UniGeneName: Cyclin-dependent kinase inhibitor 1A (p21, Cip1)
GeneOntologyID:
ENSG: ENSG00000124762
ENSP: ENSP00000244741
KEGGID: hsa+1026
ApprovedSymbol2: CDKN1A
PreviousSymbols: CDKN1
NCIName: CDKN1A
Evidence:
Chromosome: 6p21.1
Status: Approved
Reactome_ID:
Aliases: P21, CIP1, WAF1, SDI1, CAP20, p21CIP1, p21Cip1/Waf1
StringSymbol: CDKN1A
StringName: cyclin-dependent kinase inhibitor 1A (p21, Cip1); May be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression

Related Pathways:

>>[Ontocancro] RIG-I
>>[Ontocancro] TGF
>>[NCI] IL10 Anti-inflammatory Signaling Pathway
>>[NCI ] G2/M checkpoint
>>[NCI] G1/S checkpoint
>>[NCI] Extrinsic Pathway for Apoptosis
>>[NCI] Regulation of DNA Replication
>>[NCI] IL6-mediated signaling events
>>[NCI] NF-kappaB pathway
>>[BioCarta] Cyclins and Cell Cycle Regulation
>>[Reactome] S Phase
>>[Reactome] Cell Cycle, Mitotic
>>[Reactome] G1/S DNA Damage Checkpoints
>>[Reactome] Cell Cycle Checkpoints

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