EntrezGene = 1027

ID: 1027
ApprovedSymbol: CDKN1B
EntrezGene: 1027
HGNC: HGNC:1785
UniGeneID: Hs.238990
HugoName: cyclin-dependent kinase inhibitor 1B (p27, Kip1)
UniGeneName: Cyclin-dependent kinase inhibitor 1B (p27, Kip1)
GeneOntologyID: GO:0006917
ENSG: ENSG00000111276
ENSP: ENSP00000228872
KEGGID: hsa+1027
ApprovedSymbol2: CDKN1B
PreviousSymbols:
NCIName: CDKN1B
Evidence: IDA
Chromosome: 12p13.1-p12
Status: Approved
Reactome_ID:
Aliases: KIP1, P27KIP1
StringSymbol: KIP1
StringName: cyclin-dependent kinase inhibitor 1B (p27, Kip1); Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Positive regulator of cyclin D-dependent kinases such as CDK4. Regulated by phosphorylation and degradation events

Related Pathways:

>>[NCI ] G2/M checkpoint
>>[NCI] G1/S checkpoint
>>[BioCarta] Cyclins and Cell Cycle Regulation
>>[Reactome] S Phase
>>[Reactome] Cell Cycle, Mitotic
>>[Reactome] G1/S DNA Damage Checkpoints
>>[Reactome] Cell Cycle Checkpoints

Quick Links