EntrezGene = 1062

ID: 1062
ApprovedSymbol: CENPE
EntrezGene: 1062
HGNC: HGNC:1856
UniGeneID: Hs.75573
HugoName: centromere protein E, 312kDa
UniGeneName: Centromere protein E, 312kDa
GeneOntologyID:
ENSG: ENSG00000138778
ENSP: ENSP00000265148
KEGGID:
ApprovedSymbol2: CENPE
PreviousSymbols:
NCIName: CENPE
Evidence:
Chromosome: 4q24-q25
Status: Approved
Reactome_ID:
Aliases: KIF10
StringSymbol: KIF10
StringName: centromere protein E, 312kDa; Essential for the maintenance of chromosomal stability through efficient stabilization of microtubule capture at kinetochores. Plays a key role in the movement of chromosomes toward the metaphase plate during mitosis. Is a slow plus end- directed motor whose activity is essential for metaphase chromosome alignment. Couples chromosome position to microtubule depolymerizing activity. The highly processive microtubule- dependent motor activity of CENPE serves to power chromosome congression and provides a flexible, motile tether linking kinetochores to dynami [...]

Related Pathways:

>>[Reactome] Cell Cycle, Mitotic
>>[Reactome] Mitotic Spindle Checkpoint

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