EntrezGene = 1540

ID: 1540
ApprovedSymbol: CYLD
EntrezGene: 1540
HGNC: HGNC:2584
UniGeneID:
HugoName: cylindromatosis (turban tumor syndrome)
UniGeneName:
GeneOntologyID:
ENSG:
ENSP: ENSP00000308928
KEGGID:
ApprovedSymbol2: CYLD
PreviousSymbols: CYLD1
NCIName:
Evidence:
Chromosome: 16q12-q13
Status: Approved
Reactome_ID:
Aliases: KIAA0849, USPL2
StringSymbol:
StringName: cylindromatosis (turban tumor syndrome); Negative regulator of TRAF2 and NF-kappa-B signaling pathway. Has deubiquitinating activity that is directed towards non-'Lys-48'-linked polyubiquitin chains. The inhibition of NF- kappa-B activation is mediated at least in part, by the deubiquitination and inactivation of TRAF2 and, to a lesser extent, TRAF6

Related Pathways:

>>[NCI] Canonical NF-kappaB
>>[NCI] Regulation_of_p38-alpha_and_p38-beta
>>[BioCarta] tnfr1 Signaling Pathway

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