EntrezGene = 1643

ID: 1643
ApprovedSymbol: DDB2
EntrezGene: 1643
UniGeneID: Hs.708067
HugoName: damage-specific DNA binding protein 2, 48kDa
UniGeneName: Damage-specific DNA binding protein 2, 48kDa
GeneOntologyID: GO:0000718
ENSG: ENSG00000134574
ENSP: ENSP00000256996
KEGGID: hsa+1643
ApprovedSymbol2: DDB2
Evidence: EXP
Chromosome: 11p12-p11
Status: Approved
Aliases: DDBB, UV-DDB2, FLJ34321
StringSymbol: DDB2
StringName: damage-specific DNA binding protein 2, 48kDa; Required for DNA repair. Binds to DDB1 to form the UV- damaged DNA-binding protein complex (the UV-DDB complex). The UV- DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair. The UV-DDB complex preferentially binds to cyclobutane pyrimidine dimers (CPD), 6-4 photoproducts (6-4 PP), apurinic sites and short mismatches. Also appears to function as the substrate recognition module for the DCX (DDB1- CUL4-X-box) E3 ubiquitin-protein ligase complex [...]

Related Pathways:

>>[Reactome] Mismatch Repair

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