EntrezGene = 1677

ID: 1677
ApprovedSymbol: DFFB
EntrezGene: 1677
HGNC: HGNC:2773
UniGeneID: Hs.133089
HugoName: DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
UniGeneName: DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
GeneOntologyID: GO:0006309 GO:0030263
ENSG: ENSG00000169598
ENSP: ENSP00000367454
KEGGID: hsa+1677
ApprovedSymbol2: DFFB
PreviousSymbols:
NCIName: DFFB
Evidence: IDA
Chromosome: 1p36.3
Status: Approved
Reactome_ID:
Aliases: CAD, CPAN, DFF-40, DFF40
StringSymbol: DFFB
StringName: DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase); Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology

Related Pathways:

>>[NCI] Death Receptor Signalling
>>[NCI] Intrinsic Pathway for Apoptosis
>>[NCI] Apoptotic Execution Phase
>>[BioCarta] Apoptotic signaling in response to dna damage
>>[BioCarta] Induction of apoptosis through dr3 and dr4/5 death receptors
>>[BioCarta] Granzyme a Mediated Apoptosis Pathway

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