EntrezGene = 1968

ID: 1968
ApprovedSymbol: EIF2S3
EntrezGene: 1968
HGNC: HGNC:3267
UniGeneID:
HugoName: eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
UniGeneName:
GeneOntologyID:
ENSG: ENSG00000130741
ENSP: ENSP00000253039
KEGGID:
ApprovedSymbol2: EIF2S3
PreviousSymbols: EIF2G
NCIName:
Evidence:
Chromosome: Xp22.2-p22.1
Status: Approved
Reactome_ID:
Aliases: EIF2gamma, EIF2
StringSymbol:
StringName: eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a re [...]

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