EntrezGene = 207

ID: 207
ApprovedSymbol: AKT1
EntrezGene: 207
HGNC: HGNC:391
UniGeneID: Hs.525622
HugoName: v-akt murine thymoma viral oncogene homolog 1
UniGeneName: V-akt murine thymoma viral oncogene homolog 1
GeneOntologyID: GO:0006924 GO:0008633
ENSG: ENSG00000142208
ENSP: ENSP00000270202
KEGGID: hsa+207
ApprovedSymbol2: AKT1
PreviousSymbols:
NCIName: AKT1
Evidence: EXP IMP
Chromosome: 14q32.32-q32.33
Status: Approved
Reactome_ID: REACT_578
Aliases: RAC, PKB, PRKBA, AKT
StringSymbol: AKT1
StringName: v-akt murine thymoma viral oncogene homolog 1; General protein kinase capable of phosphorylating several known proteins. Phosphorylates TBC1D4. Signals downstream of phosphatidylinositol 3-kinase (PI(3)K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), insulin and insulin-like growth factor I (IGF-I). Plays a role in glucose transport by mediating insulin-induced translocation of the GLUT4 glucose transporter to the cell surface. Mediates the antiapoptotic effects of IGF-I. Mediates insulin-stimulated protei [...]

Related Pathways:

>>[Ontocancro] TGF
>>[NCI] IL8- and CXCR2-mediated signaling events
>>[NCI] IL8- and CXCR1-mediated signaling events
>>[NCI] IL10 Anti-inflammatory Signaling Pathway
>>[NCI] mtor signaling
>>[NCI] TNF Receptor Signaling Pathway
>>[BioCarta] Apoptotic signaling in response to dna damage
>>[Reactome] Apoptosis - Homo sapiens (human)

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