EntrezGene = 2071

ID: 2071
ApprovedSymbol: ERCC3
EntrezGene: 2071
HGNC: HGNC:3435
UniGeneID: Hs.469872
HugoName: excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)
UniGeneName: Excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)
GeneOntologyID: GO:0000718 GO:0006283 GO:0006917 GO:0033683
ENSG: ENSG00000163161
ENSP: ENSP00000285398
KEGGID: hsa+2071
ApprovedSymbol2: ERCC3
PreviousSymbols:
NCIName: ERCC3
Evidence: EXP IDA IDA, IMP IMP
Chromosome: 2q21
Status: Approved
Reactome_ID: REACT_1675 REACT_1788 REACT_216 REACT_6185 REACT_71
Aliases: XPB, BTF2, RAD25, TFIIH, GTF2H
StringSymbol: XPB
StringName: excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing); ATP-dependent 3'-5' DNA helicase, component of the core- TFIIH basal transcription factor, involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Acts by opening DNA either around the RNA transcription start site or the DNA damage

Related Pathways:

>>[Reactome] Mismatch Repair

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