EntrezGene = 2237

ID: 2237
ApprovedSymbol: FEN1
EntrezGene: 2237
HGNC: HGNC:3650
UniGeneID: Hs.409065
HugoName: flap structure-specific endonuclease 1
UniGeneName: Flap structure-specific endonuclease 1
GeneOntologyID:
ENSG: ENSG00000168496
ENSP: ENSP00000305480
KEGGID: hsa+2237
ApprovedSymbol2: FEN1
PreviousSymbols: RAD2
NCIName: FEN1
Evidence:
Chromosome: 11q12
Status: Approved
Reactome_ID:
Aliases: FEN-1, MF1
StringSymbol: RAD2
StringName: flap structure-specific endonuclease 1; Endonuclease that cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Also possesses 5' to 3' exonuclease activity on niked or gapped double-stranded DNA, and exhibits RNase H activity

Related Pathways:

>>[NCI] Nucleotide Excision Repair
>>[Reactome] S Phase
>>[Reactome] Cell Cycle, Mitotic

Quick Links