EntrezGene = 22897

ID: 22897
ApprovedSymbol: CEP164
EntrezGene: 22897
HGNC: HGNC:29182
UniGeneID:
HugoName: centrosomal protein 164kDa
UniGeneName:
GeneOntologyID:
ENSG: ENSG00000110274
ENSP: ENSP00000278935
KEGGID:
ApprovedSymbol2: CEP164
PreviousSymbols:
NCIName:
Evidence:
Chromosome: 11q23.3
Status: Approved
Reactome_ID:
Aliases: KIAA1052
StringSymbol:
StringName: centrosomal protein 164kDa; Plays a role in microtubule organization and/or maintenance for the formation of primary cilia (PC), a microtubule-based structure that protrudes from the surface of epithelial cells. Plays a critical role in G2/M checkpoint and nuclear divisions. A key player in the DNA damage-activated ATR/ATM signaling cascade since it is required for the proper phosphorylation of H2AX, RPA,CHK2 and CHK1. Plays a critical role in chromosome segregation, acting as a mediator required for the maintenance of genomic stability through modulation of MDC1, RPA and CHK1

Related Pathways:

>>[NCI] ATR signaling
>>[Reactome] Mitotic M-M/G1 Phases
>>[Reactome] Cell Cycle, Mitotic

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