EntrezGene = 246184

ID: 246184
ApprovedSymbol: CDC26
EntrezGene: 246184
HGNC: HGNC:17839
UniGeneID: Hs.530284
HugoName: cell division cycle 26 homolog (S. cerevisiae)
UniGeneName: Cell division cycle 26 homolog (S. cerevisiae)
ENSG: ENSG00000176386
ENSP: ENSP00000363322
KEGGID: hsa+246184
ApprovedSymbol2: CDC26
PreviousSymbols: C9orf17
NCIName: CDC26
Chromosome: 9q32
Status: Approved
StringSymbol: CDC26
StringName: cell division cycle 26 homolog (S. cerevisiae); Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex

Related Pathways:

>>[BioCarta] Rb Tumor suppressor/Check. P. Sign. in Response to Damage
>>[Reactome] Regulation of Mitotic Cell Cycle
>>[Reactome] Cell Cycle, Mitotic
>>[Reactome] Cell Cycle Checkpoints

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