EntrezGene = 2932

ID: 2932
ApprovedSymbol: GSK3B
EntrezGene: 2932
HGNC: HGNC:4617
UniGeneID: Hs.445733
HugoName: glycogen synthase kinase 3 beta
UniGeneName: Glycogen synthase kinase 3 beta
GeneOntologyID: GO:0043066
ENSG: ENSG00000082701
ENSP: ENSP00000324806
KEGGID: hsa+2932
ApprovedSymbol2: GSK3B
PreviousSymbols:
NCIName: GSK3B
Evidence: IDA
Chromosome: 3q13.3
Status: Approved
Reactome_ID: REACT_11045
Aliases:
StringSymbol: GSK3B
StringName: glycogen synthase kinase 3 beta; Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Phosphorylates MUC1 in breast cancer cells, and decreases the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin

Related Pathways:

>>[Ontocancro] TGF
>>[NCI] IL10 Anti-inflammatory Signaling Pathway
>>[NCI] G1/S checkpoint
>>[NCI] IL6-mediated signaling events

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