EntrezGene = 3551

ID: 3551
ApprovedSymbol: IKBKB
EntrezGene: 3551
HGNC: HGNC:5960
UniGeneID: Hs.656458
HugoName: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
UniGeneName: Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
GeneOntologyID:
ENSG: ENSG00000104365
ENSP: ENSP00000339151
KEGGID: hsa+3551
ApprovedSymbol2: IKBKB
PreviousSymbols:
NCIName: IKBKB
Evidence:
Chromosome: 8p11.2
Status: Approved
Reactome_ID: REACT_6900
Aliases: IKK2, NFKBIKB, IKK-beta, IKKB
StringSymbol: IKKB
StringName: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; Acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF- kappa-B complex and ultimately the degradation of the inhibitor. Also phosphorylates NCOA3

Related Pathways:

>>[Ontocancro] RIG-I
>>[Ontocancro] TGF
>>[NCI] Canonical NF-kappaB
>>[NCI] Regulation_of_p38-alpha_and_p38-beta
>>[BioCarta] Apoptotic signaling in response to dna damage
>>[Articles] Nemo

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