EntrezGene = 356

ID: 356
ApprovedSymbol: FASLG
EntrezGene: 356
HGNC: HGNC:11936
UniGeneID: Hs.2007
HugoName: Fas ligand (TNF superfamily, member 6)
UniGeneName: Fas ligand (TNF superfamily, member 6)
GeneOntologyID: GO:0008624 GO:0008633
ENSG: ENSG00000117560
ENSP: ENSP00000356694
KEGGID: hsa+356
ApprovedSymbol2: FASLG
PreviousSymbols: APT1LG1, TNFSF6
Evidence: EXP
Chromosome: 1q23
Status: Approved
Reactome_ID: REACT_578
Aliases: FasL, CD178
StringSymbol: FASLG
StringName: Fas ligand (TNF superfamily, member 6); Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects

Related Pathways:

>>[NCI] tnfr2 Signaling Pathway
>>[NCI] Regulation of Apoptosis
>>[BioCarta] Apoptotic signaling in response to dna damage

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