EntrezGene = 3646

ID: 3646
ApprovedSymbol: EIF3E
EntrezGene: 3646
HGNC: HGNC:3277
UniGeneID:
HugoName: eukaryotic translation initiation factor 3, subunit E
UniGeneName:
GeneOntologyID:
ENSG: ENSG00000104408
ENSP: ENSP00000220849
KEGGID:
ApprovedSymbol2: EIF3E
PreviousSymbols: INT6, EIF3S6
NCIName:
Evidence:
Chromosome: 8q22-q23
Status: Approved
Reactome_ID:
Aliases: eIF3-p48, eIF3e
StringSymbol:
StringName: eukaryotic translation initiation factor 3, subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosom [...]

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