EntrezGene = 51529

ID: 51529
ApprovedSymbol: ANAPC11
EntrezGene: 51529
HGNC: HGNC:14452
UniGeneID: Hs.534456
HugoName: anaphase promoting complex subunit 11
UniGeneName: APC11 anaphase promoting complex subunit 11
GeneOntologyID:
ENSG: ENSG00000141552
ENSP: ENSP00000349957
KEGGID: hsa+51529
ApprovedSymbol2: ANAPC11
PreviousSymbols:
NCIName: ANAPC11
Evidence:
Chromosome: 17q25.3
Status: Approved
Reactome_ID:
Aliases: HSPC214, APC11, Apc11p, MGC882
StringSymbol: APC11
StringName: anaphase promoting complex subunit 11; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex

Related Pathways:

>>[BioCarta] Rb Tumor suppressor/Check. P. Sign. in Response to Damage
>>[Reactome] Regulation of Mitotic Cell Cycle
>>[Reactome] Cell Cycle, Mitotic
>>[Reactome] Cell Cycle Checkpoints

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