EntrezGene = 572

ID: 572
ApprovedSymbol: BAD
EntrezGene: 572
HGNC: HGNC:936
UniGeneID: Hs.370254
HugoName: BCL2-associated agonist of cell death
UniGeneName: BCL2-associated agonist of cell death
GeneOntologyID: GO:0008633
ENSG: ENSG00000002330
ENSP: ENSP00000309103
KEGGID: hsa+572
ApprovedSymbol2: BAD
PreviousSymbols:
NCIName: BAD
Evidence: EXP
Chromosome: 11q13.1
Status: Approved
Reactome_ID: REACT_578
Aliases: BCL2L8, BBC2
StringSymbol: BAD
StringName: BCL2-associated agonist of cell death; Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways

Related Pathways:

>>[NCI] TNF Receptor Signaling Pathway
>>[BioCarta] Apoptotic signaling in response to dna damage
>>[Reactome] Apoptosis - Homo sapiens (human)

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