EntrezGene = 637

ID: 637
ApprovedSymbol: BID
EntrezGene: 637
UniGeneID: Hs.591054
HugoName: BH3 interacting domain death agonist
UniGeneName: BH3 interacting domain death agonist
GeneOntologyID: GO:0001836 GO:0008633
ENSG: ENSG00000015475
ENSP: ENSP00000318822
KEGGID: hsa+637
ApprovedSymbol2: BID
Evidence: EXP IDA
Chromosome: 22q11.2
Status: Approved
Reactome_ID: REACT_578
StringSymbol: BID
StringName: BH3 interacting domain death agonist; The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2

Related Pathways:

>>[NCI] Death Receptor Signalling
>>[NCI] TNF Receptor Signaling Pathway
>>[BioCarta] Apoptotic signaling in response to dna damage
>>[BioCarta] Induction of apoptosis through dr3 and dr4/5 death receptors
>>[Reactome] Apoptosis - Homo sapiens (human)

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