EntrezGene = 64421

ID: 64421
ApprovedSymbol: DCLRE1C
EntrezGene: 64421
HGNC: HGNC:17642
UniGeneID: Hs.656065
HugoName: DNA cross-link repair 1C (PSO2 homolog, S. cerevisiae)
UniGeneName: DNA cross-link repair 1C (PSO2 homolog, S. cerevisiae)
GeneOntologyID:
ENSG: ENSG00000152457
ENSP: ENSP00000367527
KEGGID: hsa+64421
ApprovedSymbol2: DCLRE1C
PreviousSymbols: SCIDA
NCIName: DCLRE1C
Evidence:
Chromosome: 10p13
Status: Approved
Reactome_ID:
Aliases: ARTEMIS, FLJ11360, SNM1C, A-SCID
StringSymbol: DCLRE1C
StringName: DNA cross-link repair 1C (PSO2 homolog, S. cerevisiae); Required for V(D)J recombination, the process by which exons encoding the antigen-binding domains of immunoglobulins and T-cell receptor proteins are assembled from individual V, (D), and J gene segments. V(D)J recombination is initiated by the lymphoid specific RAG endonuclease complex, which generates site specific DNA double strand breaks (DSBs). These DSBs present two types of DNA end structures: hairpin sealed coding ends and phosphorylated blunt signal ends. These ends are independently repaired by the non homologous end joi [...]

Related Pathways:

>>[NCI] Nucleotide Excision Repair

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