EntrezGene = 64682

ID: 64682
ApprovedSymbol: ANAPC1
EntrezGene: 64682
HGNC: HGNC:19988
UniGeneID: Hs.436527
HugoName: anaphase promoting complex subunit 1
UniGeneName: Anaphase promoting complex subunit 1
ENSG: ENSG00000153107
ENSP: ENSP00000339109
KEGGID: hsa+64682
ApprovedSymbol2: ANAPC1
Chromosome: 2q12.1
Status: Approved
Aliases: MCPR, TSG24, APC1
StringSymbol: ANAPC1
StringName: anaphase promoting complex subunit 1; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains

Related Pathways:

>>[BioCarta] Rb Tumor suppressor/Check. P. Sign. in Response to Damage
>>[Reactome] Regulation of Mitotic Cell Cycle
>>[Reactome] Cell Cycle, Mitotic
>>[Reactome] Cell Cycle Checkpoints

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