EntrezGene = 6868

ID: 6868
ApprovedSymbol: ADAM17
EntrezGene: 6868
HGNC: HGNC:195
UniGeneID:
HugoName: ADAM metallopeptidase domain 17
UniGeneName:
GeneOntologyID:
ENSG: ENSG00000151694
ENSP: ENSP00000309968
KEGGID:
ApprovedSymbol2: ADAM17
PreviousSymbols: TACE
NCIName:
Evidence:
Chromosome: 2p25
Status: Approved
Reactome_ID:
Aliases: cSVP, CD156B
StringSymbol:
StringName: ADAM metallopeptidase domain 17; Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Also involved in the activation of Notch pathway (By similarity)

Related Pathways:

>>[BioCarta] tnfr1 Signaling Pathway

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