EntrezGene = 840

ID: 840
ApprovedSymbol: CASP7
EntrezGene: 840
HGNC: HGNC:1508
UniGeneID: Hs.9216
HugoName: caspase 7, apoptosis-related cysteine peptidase
UniGeneName: Caspase 7, apoptosis-related cysteine peptidase
GeneOntologyID:
ENSG: ENSG00000165806
ENSP: ENSP00000298700
KEGGID: hsa+840
ApprovedSymbol2: CASP7
PreviousSymbols:
NCIName: CASP7
Evidence:
Chromosome: 10q25
Status: Approved
Reactome_ID: REACT_578
Aliases: MCH3, CMH-1, ICE-LAP3
StringSymbol: CASP7
StringName: caspase 7, apoptosis-related cysteine peptidase; Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly- 217' bond. Overexpression promotes programmed cell death

Related Pathways:

>>[NCI] Death Receptor Signalling
>>[NCI] Intrinsic Pathway for Apoptosis
>>[NCI] TNF Receptor Signaling Pathway
>>[BioCarta] Apoptotic signaling in response to dna damage
>>[BioCarta] Induction of apoptosis through dr3 and dr4/5 death receptors
>>[Reactome] Apoptosis - Homo sapiens (human)

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