EntrezGene = 8517

ID: 8517
ApprovedSymbol: IKBKG
EntrezGene: 8517
HGNC: HGNC:5961
UniGeneID: Hs.43505
HugoName: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
UniGeneName: Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
GeneOntologyID:
ENSG: ENSG00000073009
ENSP: ENSP00000358622
KEGGID: hsa+8517
ApprovedSymbol2: IKBKG
PreviousSymbols: IP2, IP1
NCIName: IKBKG
Evidence:
Chromosome: Xq28
Status: Approved
Reactome_ID: REACT_6900
Aliases: IKK-gamma, NEMO, Fip3p, FIP-3, FIP3
StringSymbol: IKBKG
StringName: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma; Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa- B-mediated protection from cytokine toxicity (By similarity)

Related Pathways:

>>[Ontocancro] TGF
>>[NCI] Canonical NF-kappaB
>>[NCI] Regulation_of_p38-alpha_and_p38-beta
>>[NCI] p53
>>[BioCarta] Apoptotic signaling in response to dna damage
>>[Articles] Nemo

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