EntrezGene = 8663

ID: 8663
ApprovedSymbol: EIF3C
EntrezGene: 8663
HGNC: HGNC:3279
UniGeneID:
HugoName: eukaryotic translation initiation factor 3, subunit C
UniGeneName:
GeneOntologyID:
ENSG:
ENSP: ENSP00000332604
KEGGID:
ApprovedSymbol2: EIF3C
PreviousSymbols: EIF3S8
NCIName:
Evidence:
Chromosome: 16p11.2
Status: Approved
Reactome_ID:
Aliases: eIF3-p110, eIF3c
StringSymbol:
StringName: eukaryotic translation initiation factor 3, subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosom [...]

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