EntrezGene = 8894

ID: 8894
ApprovedSymbol: EIF2S2
EntrezGene: 8894
HGNC: HGNC:3266
UniGeneID:
HugoName: eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
UniGeneName:
GeneOntologyID:
ENSG: ENSG00000125977
ENSP: ENSP00000364119
KEGGID:
ApprovedSymbol2: EIF2S2
PreviousSymbols: EIF2
NCIName:
Evidence:
Chromosome: 20q11.2
Status: Approved
Reactome_ID:
Aliases: EIF2beta
StringSymbol:
StringName: eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA (By similarity). This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex (By similarity). Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex (By similarity). In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound [...]

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