EntrezGene = 8945

ID: 8945
ApprovedSymbol: BTRC
EntrezGene: 8945
HGNC: HGNC:1144
UniGeneID: Hs.643802
HugoName: beta-transducin repeat containing
UniGeneName: Beta-transducin repeat containing
GeneOntologyID:
ENSG: ENSG00000166167
ENSP: ENSP00000359206
KEGGID:
ApprovedSymbol2: BTRC
PreviousSymbols:
NCIName: BTRC
Evidence:
Chromosome: 10q24.32
Status: Approved
Reactome_ID:
Aliases: bTrCP, betaTrCP, FBXW1A, Fwd1, beta-TrCP1, bTrCP1
StringSymbol: BTRC
StringName: beta-transducin repeat containing; Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. SCF(BTRC) mediates the ubiquitination of CTNNB1 and participates in Wnt signaling. SCF(BTRC) mediates the ubiquitination of NFKBIA, NFKBIB and NFKBIE; the degradation frees the associated NFKB1 to translocate into the nucleus and to activate transcription. SCF(BTRC) mediates the ubiquitination [...]

Related Pathways:

>>[Reactome] Regulation of Mitotic Cell Cycle
>>[Reactome] Cell Cycle, Mitotic

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