EntrezGene = 9212

ID: 9212
ApprovedSymbol: AURKB
EntrezGene: 9212
HGNC: HGNC:11390
UniGeneID: Hs.442658
HugoName: aurora kinase B
UniGeneName: Aurora kinase B
ENSG: ENSG00000178999
ENSP: ENSP00000313950
ApprovedSymbol2: AURKB
PreviousSymbols: STK12
Chromosome: 17p13.1
Status: Approved
Aliases: Aik2, IPL1, AurB, AIM-1, ARK2, STK5
StringSymbol: AURKB
StringName: aurora kinase B; May be directly involved in regulating the cleavage of polar spindle microtubules and is a key regulator for the onset of cytokinesis during mitosis. Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Phosphorylates 'Ser-10' and 'Ser-28' of histone H3 during mitosis

Related Pathways:

>>[Reactome] Regulation of Mitotic Cell Cycle
>>[Reactome] Cell Cycle, Mitotic
>>[Reactome] Mitotic Spindle Checkpoint

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