EntrezGene = 996

ID: 996
ApprovedSymbol: CDC27
EntrezGene: 996
UniGeneID: Hs.463295
HugoName: cell division cycle 27 homolog (S. cerevisiae)
UniGeneName: Cell division cycle 27 homolog (S. cerevisiae)
ENSG: ENSG00000004897
ENSP: ENSP00000399255
KEGGID: hsa+996
ApprovedSymbol2: CDC27
PreviousSymbols: D0S1430E, D17S978E
NCIName: CDC27
Chromosome: 17q21.32
Status: Approved
Aliases: APC3
StringSymbol: APC3
StringName: cell division cycle 27 homolog (S. cerevisiae); Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains

Related Pathways:

>>[BioCarta] Rb Tumor suppressor/Check. P. Sign. in Response to Damage
>>[Reactome] Regulation of Mitotic Cell Cycle
>>[Reactome] Cell Cycle, Mitotic
>>[Reactome] Cell Cycle Checkpoints

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