NAME: TNF

ID ApprovedSymbol EntrezGene HGNC UniGeneID Affymetrics HugoName UniGeneName GeneOntologyID ENSG ENSP KEGGID ApprovedSymbol2 PreviousSymbols NCIName Evidence Chromosome Status Reactome_ID Aliases StringSymbol StringName
466 ATF1 466 HGNC:783 1558233_s_at
1565269_s_at
222103_at
activating transcription factor 1 ENSG00000123268 12q13 Approved
1386 ATF2 1386 HGNC:784 1555146_at
205446_s_at
212984_at
activating transcription factor 2 ENSG00000115966 CREB2 2q32 Approved
22926 ATF6 22926 HGNC:791 203952_at
217550_at
226941_at
231927_at
activating transcription factor 6 ENSG00000118217 1q22-q23 Approved
1051 CEBPB 1051 HGNC:1834 212501_at
CCAAT/enhancer binding protein (C/EBP), beta ENSG00000172216 TCF5 20q13.1 Approved
1385 CREB1 1385 HGNC:2345 204312_x_at
204313_s_at
204314_s_at
214513_s_at
225565_at
225572_at
237289_at
cAMP responsive element binding protein 1 ENSG00000118260 2q34 Approved
1457 CSNK2A1 1457 HGNC:2457 206075_s_at
212072_s_at
212073_at
212075_s_at
229216_s_at
casein kinase 2, alpha 1 polypeptide ENSG00000101266 CSNK2A1 20p13 Approved
1649 DDIT3 1649 HGNC:2726 209383_at
DNA-damage-inducible transcript 3 12q13.1-q13.2 Approved
1673 DEFB4A 1673 HGNC:2767 207356_at
defensin, beta 4A ENSG00000171711 DEFB102, DEFB2, DEFB4 8p23.1 Approved
1977 EIF4E 1977 HGNC:3287 201435_s_at
201436_at
201437_s_at
237718_at
242674_at
eukaryotic translation initiation factor 4E ENSG00000151247 ENSP00000280892 EIF4E EIF4EL1, EIF4F 4q21-q25 Approved EIF4E1 eukaryotic translation initiation factor 4E; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures
1978 EIF4EBP1 1978 HGNC:3288 221539_at
eukaryotic translation initiation factor 4E binding protein 1 ENSG00000187840 8p12 Approved
2099 ESR1 2099 HGNC:3467 205225_at
211233_x_at
211234_x_at
211235_s_at
211627_x_at
215552_s_at
217163_at
217190_x_at
estrogen receptor 1 ENSG00000091831 ESR1 ESR 6q24-q27 Approved
2664 GDI1 2664 HGNC:4226 201864_at
GDP dissociation inhibitor 1 ENSG00000203879 MRX48, MRX41, GDIL Xq28 Approved
26959 HBP1 26959 HGNC:23200 207361_at
209102_s_at
HMG-box transcription factor 1 ENSG00000105856 7q22-q31 Approved
3315 HSPB1 3315 HGNC:5246 201841_s_at
heat shock 27kDa protein 1 ENSG00000106211 7q11.23 Approved
3725 JUN 3725 HGNC:6204 201464_x_at
201465_s_at
201466_s_at
213281_at
jun proto-oncogene ENSG00000177606 1p32-p31 Approved
3880 KRT19 3880 HGNC:6436 201650_at
228491_at
keratin 19 ENSG00000171345 17q21.2 Approved
3856 KRT8 3856 HGNC:6446 209008_x_at
216821_at
keratin 8 ENSG00000170421 12q13.13 Approved
5600 MAPK11 5600 HGNC:6873 206040_s_at
211499_s_at
211500_at
mitogen-activated protein kinase 11 ENSG00000185386 MAPK11 PRKM11 22q13.33 Approved
1432 MAPK14 1432 HGNC:6876 Hs.588289 202530_at
210449_x_at
211087_x_at
211561_x_at
mitogen-activated protein kinase 14 Mitogen-activated protein kinase 14 ENSG00000112062 ENSP00000229794 MAPK14 CSPB1, CSBP1, CSBP2 MAPK14 6p21.3-p21.2 Approved PRKM14, p38, Mxi2, PRKM15 Mxi2 mitogen-activated protein kinase 14; Responds to activation by environmental stress, pro- inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset o [...]
9261 MAPKAPK2 9261 HGNC:6887 201460_at
201461_s_at
215050_x_at
mitogen-activated protein kinase-activated protein kinase 2 ENSG00000162889 MAPKAPK2 1q32 Approved
7867 MAPKAPK3 7867 HGNC:6888 202787_s_at
202788_at
mitogen-activated protein kinase-activated protein kinase 3 ENSG00000114738 3p21.3 Approved
8550 MAPKAPK5 8550 HGNC:6889 212871_at
mitogen-activated protein kinase-activated protein kinase 5 ENSG00000089022 12q24.13 Approved
4205 MEF2A 4205 HGNC:6993 myocyte enhancer factor 2A 15q26 Approved
4208 MEF2C 4208 HGNC:6996 207968_s_at
209199_s_at
209200_at
myocyte enhancer factor 2C ENSG00000081189 5q14.3 Approved
4286 MITF 4286 HGNC:7105 1554874_at
207233_s_at
226066_at
microphthalmia-associated transcription factor ENSG00000187098 WS2A, WS2 3p14.1-p12.3 Approved
8569 MKNK1 8569 HGNC:7110 1560720_at
209467_s_at
243256_at
MAP kinase interacting serine/threonine kinase 1 ENSG00000079277 1p33 Approved
4843 NOS2 4843 HGNC:7873 210037_s_at
nitric oxide synthase 2, inducible ENSG00000007171 NOS2A 17q11.2-q12 Approved
5321 PLA2G4A 5321 HGNC:9035 210145_at
phospholipase A2, group IVA (cytosolic, calcium-dependent) ENSG00000116711 PLA2G4 1q25 Approved
10891 PPARGC1A 10891 HGNC:9237 1569141_a_at
219195_at
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha ENSG00000109819 PPARGC1 4p15.1 Approved
8986 RPS6KA4 8986 HGNC:10433 204632_at
230544_at
ribosomal protein S6 kinase, 90kDa, polypeptide 4 ENSG00000162302 11q11-q13 Approved
9252 RPS6KA5 9252 HGNC:10434 1554319_at
204633_s_at
204635_at
ribosomal protein S6 kinase, 90kDa, polypeptide 5 14q31-q32.1 Approved
6548 SLC9A1 6548 HGNC:11071 1554728_at
209453_at
solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 ENSG00000090020 APNH, NHE1 1p36.1-p35 Approved
7157 TP53 7157 HGNC:11998 Hs.654481 201746_at
211300_s_at
tumor protein p53 Tumor protein p53 GO:0006289 GO:0008635 GO:0042771 ENSG00000141510 ENSP00000269305 hsa+7157 TP53 TP53 IDA IMP 17p13.1 Approved REACT_1538 p53, LFS1 P53 tumor protein p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over
7391 USF1 7391 HGNC:12593 231768_at
upstream transcription factor 1 ENSG00000158773 1q22-q23 Approved
34 genes found.

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ID ApprovedSymbol EntrezGene HGNC
UniGeneID HugoName UniGeneName GeneOntologyID
ENSG ENSP KEGGID ApprovedSymbol2
PreviousSymbols NCIName Evidence Chromosome
Status Reactome_ID Aliases StringSymbol
StringName Affymetrics


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