NAME: nf-kb signaling

ID ApprovedSymbol EntrezGene HGNC UniGeneID Affymetrics HugoName UniGeneName GeneOntologyID ENSG ENSP KEGGID ApprovedSymbol2 PreviousSymbols NCIName Evidence Chromosome Status Reactome_ID Aliases StringSymbol StringName
644 BLVRA 644 HGNC:1062 203771_s_at
203772_at
203773_x_at
211729_x_at
229109_s_at
biliverdin reductase A ENSG00000106605 BLVR 7p13 Approved
645 BLVRB 645 HGNC:1063 202201_at
biliverdin reductase B (flavin reductase (NADPH)) FLR 19q13.1-q13.2 Approved
3162 HMOX1 3162 HGNC:5013 203665_at
heme oxygenase (decycling) 1 ENSG00000100292 22q12 Approved
3586 IL10 3586 HGNC:5962 207433_at
interleukin 10 ENSG00000136634 1q31-q32 Approved
3587 IL10RA 3587 HGNC:5964 204912_at
interleukin 10 receptor, alpha ENSG00000110324 IL10R 11q23 Approved
3588 IL10RB 3588 HGNC:5965 209575_at
interleukin 10 receptor, beta ENSG00000243646 CRFB4, D21S58, D21S66 21q22.11 Approved
3552 IL1A 3552 HGNC:5991 Hs.1722 208200_at
210118_s_at
interleukin 1, alpha Interleukin 1, alpha ENSG00000115008 ENSP00000263339 hsa+3552 IL1A IL1 IL1A 2q14 Approved IL1F1, IL-1A IL1 interleukin 1, alpha; Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity)
3569 IL6 3569 HGNC:6018 205207_at
interleukin 6 ENSG00000136244 IFNB2 7p21-p15 Approved
3716 JAK1 3716 HGNC:6190 1552610_a_at
1552611_a_at
1562103_at
201648_at
239695_at
240613_at
Janus kinase 1 ENSG00000162434 JAK1B 1p32.3-p31.3 Approved
6772 STAT1 6772 HGNC:11362 Hs.642990 200887_s_at
209969_s_at
AFFX-HUMISGF3A-M97935_3_at
AFFX-HUMISGF3A-M97935_5_at
AFFX-HUMISGF3A-M97935_MA_at
AFFX-HUMISGF3A-M97935_MB_at
signal transducer and activator of transcription 1, 91kDa Signal transducer and activator of transcription 1, 91kDa ENSG00000115415 ENSP00000354394 STAT1 STAT1 2q32.2-q32.3 Approved STAT91, ISGF-3 STAT1 signal transducer and activator of transcription 1, 91kDa; Signal transducer and activator of transcription that mediates signaling by interferons (IFNs). Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated gen [...]
6773 STAT2 6773 HGNC:11363 205170_at
217199_s_at
225636_at
signal transducer and activator of transcription 2, 113kDa 12q13.2 Approved
6775 STAT4 6775 HGNC:11365 206118_at
signal transducer and activator of transcription 4 ENSG00000138378 2q32.2-q32.3 Approved
6776 STAT5A 6776 HGNC:11366 203010_at
signal transducer and activator of transcription 5A ENSG00000126561 STAT5 17q11.2 Approved
6777 STAT5B 6777 HGNC:11367 1555086_at
1555088_x_at
205026_at
212549_at
212550_at
signal transducer and activator of transcription 5B ENSG00000173757 17q11.2 Approved
6778 STAT6 6778 HGNC:11368 201331_s_at
201332_s_at
signal transducer and activator of transcription 6, interleukin-4 induced 12q13 Approved
7124 TNF 7124 HGNC:11892 Hs.241570 207113_s_at
tumor necrosis factor (TNF superfamily, member 2) Tumor necrosis factor (TNF superfamily, member 2) GO:0006916 GO:0006919 GO:0006927 ENSG00000206439 ENSP00000392858 hsa+7124 TNF TNFA TNF IDA 6p21.3 Approved REACT_578 TNFSF2, DIF, TNF-alpha ENSG00000206439 tumor necrosis factor (TNF superfamily, member 2); Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation
16 genes found.

Pathway Download Options. Check boxes below or ALL

ID ApprovedSymbol EntrezGene HGNC
UniGeneID HugoName UniGeneName GeneOntologyID
ENSG ENSP KEGGID ApprovedSymbol2
PreviousSymbols NCIName Evidence Chromosome
Status Reactome_ID Aliases StringSymbol
StringName Affymetrics


OR


Choose Platform:

GPL 571
GPL 8300
GPL 96
GPL 570

Quick Links